Dr. Ming Zhou graduated summa cum laude from Fudan University Medical School in Shanghai, China. He completed his pathology residency training at the University of Michigan and a fellowship in the Urological and Kidney Diseases at the Johns Hopkins Hospital. He is board certified in Anatomic and Clinical Pathology.

Dr. Zhou has devoted his clinical and research effort to diagnostic urological pathology, and discovery and validation of tumor markers for urological malignancy. He has authored over 200 peer-reviewed articles and numerous book chapters, and is the co-editor of 7 textbooks of urological and prostate pathology, including the AFIP prostate fascicle. He frequently lectures at national and international meetings on urological pathology. He was the co-course director of the prostate cancer long course at the 2018 USCAP annual meeting. He is the president of Genitourinary Pathology Society (GUPS), an international urologic pathology organization.

I like to fix things around house, even when they are not broken!

7/1989 Rong-Lin Award (the highest honor bestowed upon medical graduates by Shanghai Medical University)

3/1996 Honorable Mentioning, the Graduate Research Forum,
Department of Molecular Genetics, Biochemistry and Microbiology,
University of Cincinnati College of Medicine

6/2001 Outstanding Resident in Clinical Pathology
Department of Pathology
University of Michigan Medical Center

10/2001 M.R. Abell House Officer Award
Department of Pathology
University of Michigan Medical Center

2/2002 Stowell-Orbison Award
United States and Canadian Academy of Pathology

2/2002 Autopsy Award
United States and Canadian Academy of Pathology

4/2003 Young Investigator’s Award
5th Annual Pathology Young Investigators' Symposium
Department of Pathology
The Johns Hopkins Medical Institutions

In June 2019, I became the Chair and Pathologist-in-Chief  to steer the Pathology department of one of the oldest hospitals in New England into the future. 

1. Zhou M, Sutliff R, Paul R, Lorenz J, Hoying JB, Haudenschild CC, Yin M, Coffin JD, Cong L, Kranias EG, Luo W, Boivin GP, Duffy JJ, Pawlowski SA, Doetschman T. (1998). Fibroblast growth factor 2 control of vascular tone. Nature Medicine. 4(2):201-7

2. Rubin MA, Zhou M, Dhanasekaran S, Varambally S, Barrette TR, Sanda MG, Pienta KJ, Ghosh D, Chinnaiyan AM. (2002) ?-Methylacyl-CoA racemase as a tissue biomarker for prostate cancer. JAMA 287(13):1662-1670

3. Zhou M, Yutaka, M., Sidransky, D., and Epstein, J.I. (2004) Quantitative GSTP1 methylation levels correlate with Gleason grades and tumor volume in prostate needle biopsies. J Urol (171):2195-8

4. Tamaskar I, Choueiri TK, Sercia L, Rini B, Bukowski R, Zhou M. Differential expression of caveolin-1 in renal neoplasms. Cancer. 2007 Aug; 110 (4): 776-82

5. Zhou M, Reuther AM, Levin HS, Falzarano SM, Kodjoe E, Myles J, Klein E, Magi-Galluzzi C. Microscopic bladder neck involvement by prostate carcinoma in radical prostatectomy specimens is not a significant independent prognostic factor. Mod Pathol. 2008 Nov 28. [Epub ahead of print]

6.Zhou M, Yang XJ, Lopez JI, Shah RB, Hes O, Shen SS, Li R, Yang Y, Lin F, Elson P, Sercia L, Magi-Galluzzi C, Tubbs R. Renal Tubulocystic Carcinoma Is Closely Related to Papillary Renal Cell Carcinoma: Implications for Pathologic Classification. Am J Surg Pathol. 2009 Dec;33(12):1840-9.

7. Shah RB, Magi-Galluzzi C, Han B, Zhou M. Atypical Cribriform Lesions of the Prostate: Relationship to Prostatic Carcinoma and Implication for Diagnosis in Prostate Biopsies. Am J Surg Pathol. 2010 Apr;34(4):470-7.

8. Aydin H, Chen L, Cheng L, Vaziri S, He H, Ganapathi R, Delahunt B, Magi-Galluzzi C, Zhou M. Clear Cell Tubulopapillary Renal Cell Carcinoma: A Study of 36 Distinctive Low-grade Epithelial Tumors of the Kidney. Am J Surg Pathol. 2010 Nov;34(11):1608-21

9. He H, Osunkoya AO, Carver P, Falzarano S, Klein E, Magi-Galluzzi C, Zhou M. Expression of ERG protein, a prostate cancer specific marker, in high grade prostatic intraepithelial neoplasia (HGPIN): lack of utility to stratify cancer risks associated with HGPIN. BJU Int. 2012 Dec;110(11 Pt B):E751-5

10. Yaskiv O, Rubin BP, He H, Falzarano S, Magi-Galluzzi C, Zhou M. ERG Protein Expression in Human Tumors Detected With a Rabbit Monoclonal Antibody. Am J Clin Pathol. 2012 Dec;138(6):803-10. doi: 10.1309/AJCP3K5VUFALZTKC.

11.Ding Y, Chen L, Deng FM, Melamed J, Fan R, Bonsib S, Zhou M. Localized Cystic Disease of the Kidney: Distinction From Cystic Neoplasms and Hereditary Polycystic Diseases. Am J Surg Pathol. 2013 Apr;37(4):506-13

12.Huang CC(1), Deng FM, Kong MX, Ren Q, Melamed J, Zhou M. Re-evaluating the concept of "dominant/index tumor nodule" in multifocal prostate cancer. Virchows Arch. 2014 Mar 12. [Epub ahead of print]

13. Shah RB, Li J, Cheng L, Egevad L, Deng FM, Fine SW, Kunju LP, Melamed J, Mehra R, Osunkoya AO, Paner GP, Shen SS, Tsuzuki T, Trpkov K, Tian W, Yang XJ, Zhou M. Diagnosis of Gleason Pattern 5 Prostate Adenocarcinoma on Core Needle Biopsy: An Interobserver Reproducibility Study Among Urologic Pathologists. Am J Surg Pathol. 2015 Apr 28. [Epub ahead of print]

14. Zhou, Ming; Li, Jianbo; Cheng, Liang; Egevad, Lars; Deng, Fang-Ming; Kunju, Lakshmi Priya; Magi-Galluzzi, Cristina; Melamed, Jonathan; Mehra, Rohit; Mendrinos, Savvas; Osunkoya, Adeboye O; Paner, Gladell; Shen, Steve S; Tsuzuki, Toyonori; Trpkov, Kiril; Tian, Wei; Yang, Ximing; Shah, Rajal B. 'Diagnosis of "Poorly Formed Glands" Gleason Pattern 4 Prostatic Adenocarcinoma on Needle Biopsy: An Interobserver Reproducibility Study Among Urologic Pathologists With Recommendations'. American journal of surgical pathology. 2015 ():?-? (# 1640842)

15. Peng YC, Tsuzuki T, Kong MX, Li J, Deng FM, Melamed J, Zhou M. Incidence of intraductal carcinoma, multifocality and bilateral significant disease in radical prostatectomy specimens from Japan and United States. Pathol Int. 2016 Oct 26. doi: 10.1111/pin.12469. [Epub ahead of print]

16. Zhao Y, Deng FM, Huang H, Lee P, Lepor H, Rosenkrantz AB, Taneja S, Melamed J, Zhou M. Prostate Cancers Detected by Magnetic Resonance Imaging-Targeted Biopsies Have a Higher Percentage of Gleason Pattern 4 Component and Are Less Likely to Be Upgraded in Radical Prostatectomies. Arch Pathol Lab Med. 2018 Jul 2. doi: 10.5858/arpa.2017-0410-OA. [Epub ahead of print]

Books:

1. Genitourinary Pathology, edited by Zhou M and Magi-Galluzzi C, Elsevier, Philadelphia, PA (2006)

2. Prostate Biopsy Interpretation: An Illustrated Guide, by Shah R and Zhou M, Springer-Verlag Berlin Heidelberg (2011)

3. High Yield Pathology: Uropathology, by Zhou M, Netto G, Epstein JI, Elsevier, Philadelphia, PA (2012)

4. Genitourinary Pathology, a Volume in the series Foundations in Diagnostic Pathology, 2nd edition, edited by Zhou M and Magi-Galluzzi C, Elsevier, Philadelphia, PA (2015)

Clinical Practices Guidelines:

1. John R. Srigley*; Ming Zhou*; Robert Allan; Mahul B. Amin; Steven C. Campbell; Anthony Chang; Brett Delahunt; David J. Grignon; Peter A. Humphrey; Bradley C. Leibovich; Rodolfo Montironi; Jason Pettus; Victor E. Reuter. Protocol for the Examination of Specimens from Patients with Invasive Carcinoma of Renal Tubular Origin. Published June 2017. College of American Pathologists. http://www.cap.org/ShowProperty?nodePath=/UCMCon/Contribution Folders/WebContent/pdf/cp-kidney-17protocol-4011.pdf *Primary authors

2. Antonio L. Cubilla*; Ming Zhou*; Robert Allan; Mahul B. Amin; Jonathan I. Epstein; David J. Grignon; Peter A. Humphrey; Curtis A. Pettaway; Jason Pettus; Victor E. Reuter; John R. Srigley; Elsa F. Velazquez. Protocol for the Examination of Specimens From Patients With Carcinoma of the Penis. Version: Penis 4.0.1.0. Published June 2017. College of American Pathologists. http://www.cap.org/ShowProperty?nodePath=/UCMCon/Contribution Folders/WebContent/pdf/cp-penis-17protocol-4010.pdf. *Primary authors
3. John R. Srigley*; Ming Zhou, MD*; Robert Allan; Mahul B. Amin; Sam S. Chang; Brett Delahunt; Lars Egevad; Jonathan I. Epstein; David J. Grignon; Peter A. Humphrey; James M. McKiernan; Rodolfo Montironi; Jason Pettus; Victor E. Reuter; Thomas M. Wheeler. Protocol for the Examination of Specimens From Patients With Carcinoma of the Prostate Gland. Version: Prostate 4.0.2.0. Published June 2017. College of American Pathologists. http://www.cap.org/ShowProperty?nodePath=/UCMCon/Contribution Folders/WebContent/pdf/cp-prostate-17protocol-4020.pdf *Primary authors
4. Satish K. Tickoo*; Ming Zhou*; Robert Allan; Mahul B. Amin; Sam S. Chang; Peter A. Humphrey; James McKiernan; Jason Pettus; Victor E. Reuter; John R. Srigley; Thomas M. Ulbright. Protocol for the Examination of Specimens From Patients With Malignant Germ Cell and Sex Cord-Stromal Tumors of the Testis. Version: Testis 4.0.1.0. Published June 2017. http://www.cap.org/ShowProperty?nodePath=/UCMCon/Contribution Folders/WebContent/pdf/cp-testis-17protocol-4010.pdf * Primary authors
5. Peter A. Humphrey*; Ming Zhou MD*; Robert Allan; Mahul B. Amin; Anthony Chang; Arthur H. Cohen; Brett Delahunt; Jonathan I. Epstein; David J. Grignon; Rodolfo Montironi; Jason Pettus; Victor E. Reuter; John R. Srigley. Protocol for the Examination of Specimens From Patients With Carcinoma of the Ureter and Renal Pelvis. Version: UreterRenalPelvis 2.0.1.0. Published June 2017. http://www.cap.org/ShowProperty?nodePath=/UCMCon/Contribution Folders/WebContent/pdf/cp-ureter-renalpelvis-17protocol-2100.pdf * Primary authors
6. Jesse K. McKenney*; Ming Zhou*; Robert Allan; Mahul B. Amin; Jonathan I. Epstein; David J. Grignon; Peter A. Humphrey; Esther Oliva; Jason Pettus; Victor E. Reuter; John R. Srigley. Protocol for the Examination of Specimens From Patients With Carcinoma of the Urethra and Periurethral Glands. Version: Urethra 4.0.1.1. Published June 2017. http://www.cap.org/ShowProperty?nodePath=/UCMCon/Contribution Folders/WebContent/pdf/cp-urethra-17protocol-4011.pdf * Primary authors
7. Ming Zhou, MD*; John R. Srigley*; Mahul B. Amin; Robert Allan; Brett Delahunt; Bernard H. Bochner; Jonathan I. Epstein; David J. Grignon; Peter A. Humphrey; Rodolfo Montironi; Gladell P. Paner; Jason Pettus; Victor E. Reuter. Protocol for the Examination of Specimens From Patients With Carcinoma of the Urinary Bladder. Version: UrinaryBladder 4.0.1.0. Published June 2017. http://www.cap.org/ShowProperty?nodePath=/UCMCon/Contribution Folders/WebContent/pdf/cp-urinary-bladder-17protocol-4010.pdf * Primary authors

Presentations:

1. Genitourinary Tumors: New entities, Concepts and Diagnostic Approaches. California Tumor Tissue Registry Semi-annual meeting, Costa Mesa, CA. June 1, 2014
2. Prostate Pathology: Practical Issues. USCAP long course, USCAP 106th Annual Meeting, San Antonio, TX, March 8th, 2017 (co-organizer with Dr. Cristina Magi-Galluzzi)

• Surgical Pathology of the GI, GYN and GU Tracts and Tumors of Soft Tissue and Endocrine Organs: Practical Tips for the Practicing Pathologist

Past Lectures

• Pathology of the Testis: Diagnosis You Want to Get Right (06/25/2021)
• Digital Slides: A Potpourri of GU Cases (06/24/2021)
• Pattern-Based Diagnosis and Classification of Renal Tumors (06/24/2021)
• Bladder Cancer: Practical Issues and Updates (06/23/2021)
• Prostate Cancer: Update on Grading and New Entities (06/22/2021)